Vanessa was the wife of Tim Dunlear, a retired basketball player. The couple ran the Dunlear Foundation together. However, Vanessa was embezzling funds from the foundation, and when Tim found out about it, she killed him. While under Lucifer's spell, Vanessa stated that she deserved the money for supporting Tim after his retirement and she had to kill him because he would "ruin everything."
It was also revealed that Tim was having an affair with their male assistant, which Vanessa knew about. At the foundation's latest gathering, Vanessa meets Lucifer after he was nearly shot, and she tells him that she is headed on a flight to Buenos Aires. Lucifer mentions that Argentina was where the Nazis escaped to get away with murder, and it is there that he realizes that Vanessa did kill her husband, a claim she denied. But seeing that he was not fooled, Vanessa points a gun at Lucifer and shoots him several times, leaving him (assumingly) for dead. To Vanessa's shock, Lucifer returns, alive and well, then outs Vanessa as the murderer, while Chloe appears and reveals Vanessa's embezzling scheme. Vanessa is then handcuffed and arrested for Tim's murder.